BDBM412305 US10399945, Example 40::US10669239, Compound 40

SMILES Cc1cc(NC(=O)NC2[C@H](O)CC(C)(C)c3cc(F)c(F)cc23)c(nc1C(N)=O)-c1ccccc1

InChI Key InChIKey=PYGREIRRHOFADQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 412305   

TargetHigh affinity nerve growth factor receptor(Human)
Mochida Pharmaceutical

US Patent
LigandPNGBDBM412305(US10399945, Example 40 | US10669239, Compound 40)
Affinity DataIC50: 50nMAssay Description:Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Mochida Pharmaceutical

US Patent
LigandPNGBDBM412305(US10399945, Example 40 | US10669239, Compound 40)
Affinity DataIC50: 50nMAssay Description:Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent