BDBM413223 6-(5-hydroxy-4-(2-methoxypyridin-4-yl)-1H-pyrazol-1-yl)-N-((1-(methoxymethyl)cyclopentyl)methyl)nicotinamide::US10407409, Example 47

SMILES COCC1(CNC(=O)c2ccc(nc2)-n2ncc(c2O)-c2ccnc(OC)c2)CCCC1

InChI Key InChIKey=PCQLSNCSPUWJET-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 413223   

TargetEgl nine homolog 1 [181-417](Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM413223(6-(5-hydroxy-4-(2-methoxypyridin-4-yl)-1H-pyrazol-...)
Affinity DataIC50:  3.98nMAssay Description:The IC50 values for the PHD2 enzyme (residues 181-417) were determined by mixing increasing amounts of inhibitor with a fixed amount of enzyme (5 nM,...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent