BDBM413388 US10407422, Example 185

SMILES Nc1cc(Cc2cnn(Cc3ccc(CNC4CC4)cc3)c2)c2nn[nH]c2n1

InChI Key InChIKey=KGSQHSRZPHUFFT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 413388   

TargetMyeloperoxidase(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM413388(US10407422, Example 185)
Affinity DataIC50: 45nMAssay Description:EPX bromination activity was measured in 100 mM KPi (pH 7.4) by monitoring the H2O2 catalyzed formation of 3-bromo tyrosine from tyrosine and potassi...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
US Patent