BDBM413432 2-(dipropylcarbamoyl)methyl 2-(4-{[2-amino-4-(pentylamino)-5H-pyrrolo[3,2-d]pyrimidin-5-yl]methyl}-3-methoxyphenyl)acetate::US10407431, Example 19

SMILES CCCCCNc1nc(N)nc2ccn(Cc3ccc(CC(=O)OCC(=O)N(CCC)CCC)cc3OC)c12

InChI Key InChIKey=CWZMIMVFFXBCGL-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 413432   

TargetToll-like receptor 7(Human)
Novartis

US Patent
LigandPNGBDBM413432(US10407431, Example 19 | 2-(dipropylcarbamoyl)meth...)
Affinity DataEC50:  200nMAssay Description:Human embryonic kidney 293 (HEK 293) cells were stably transfected with human TLR7 and an NF-kB-driven luciferase reporter vector (pNifty-Luciferase)...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
US Patent