BDBM413446 (S)-2-((2-amino-5-(2-methoxy-4-(piperazin-1-ylmethyl)benzyl)-5H-pyrrolo[3,2-d]pyrimidin-4-yl)amino)hexan-1-ol::US10407431, Example 33

SMILES CCCC[C@@H](CO)Nc1nc(N)nc2ccn(Cc3ccc(CN4CCNCC4)cc3OC)c12

InChI Key InChIKey=GTZVTPGTXBZOIN-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 413446   

TargetToll-like receptor 7(Human)
Novartis

US Patent
LigandPNGBDBM413446(US10407431, Example 33 | (S)-2-((2-amino-5-(2-meth...)
Affinity DataEC50:  7nMAssay Description:Human embryonic kidney 293 (HEK 293) cells were stably transfected with human TLR7 and an NF-kB-driven luciferase reporter vector (pNifty-Luciferase)...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
US Patent