BDBM413545 US10414765, Example 27

SMILES COc1cccc(c1)C(=O)N1CC2CN(Cc3c(nc4ccccn34)-c3ccc(cc3)C(C)C)CC2C1

InChI Key InChIKey=VIMXRDYIELLEAZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 413545   

TargetPotassium channel subfamily K member 3(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM413545(US10414765, Example 27)
Affinity DataIC50: 170nMAssay Description:In Vitro Electrophysiological Analysis of the Human TASK-1 and TASK-3 Channels Via Two-Electrode Voltage Clamp Technique in Xenopus laevis OocytesSub...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
8/2/2020
Entry Details
US Patent

TargetPotassium channel subfamily K member 9(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM413545(US10414765, Example 27)
Affinity DataIC50: 170nMAssay Description:In Vitro Electrophysiological Analysis of the Human TASK-1 and TASK-3 Channels Via Two-Electrode Voltage Clamp Technique in Xenopus laevis OocytesSub...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
8/2/2020
Entry Details
US Patent