BDBM413952 US10421756, Compound 136

SMILES COCCN1CCC2(C1)CCN(CC2)C(=O)Nc1cc(ccc1N)-c1ccncc1

InChI Key InChIKey=NBNQGKAPAVDJLL-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 413952   

TargetHistone deacetylase 1(Human)
Rodin Therapeutics

US Patent
LigandPNGBDBM413952(US10421756, Compound 136)
Affinity DataKd: <100nMAssay Description:HDAC2 containing a C-terminal HIS-Tag (Proteros) and fluorescently-labeled anti-HIS-antibody are diluted in one vial in assay buffer 50 mM Tris, pH 8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2020
Entry Details
US Patent

TargetHistone deacetylase 2(Human)
Rodin Therapeutics

US Patent
LigandPNGBDBM413952(US10421756, Compound 136)
Affinity DataKd:  300nMAssay Description:HDAC2 containing a C-terminal HIS-Tag (Proteros) and fluorescently-labeled anti-HIS-antibody are diluted in one vial in assay buffer 50 mM Tris, pH 8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2020
Entry Details
US Patent