BDBM414113 US10435361, Example 1

SMILES CNc1cc(cc(NC(=O)Nc2ccc(Oc3ccnc(Nc4cc(cc(c4)C(=O)NCCN4CCOCC4)C#C)n3)c3ccccc23)c1OC)C(C)(C)C

InChI Key InChIKey=VFQNGIVBLUWECA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 414113   

TargetProto-oncogene tyrosine-protein kinase Src(Human)
Topivert Pharma

US Patent
LigandPNGBDBM414113(US10435361, Example 1)
Affinity DataIC50: 12nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
Topivert Pharma

US Patent
LigandPNGBDBM414113(US10435361, Example 1)
Affinity DataIC50: 51nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
US Patent

TargetMitogen-activated protein kinase 14(Human)
Topivert Pharma

US Patent
LigandPNGBDBM414113(US10435361, Example 1)
Affinity DataIC50: 118nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
US Patent

TargetGlycogen synthase kinase-3 alpha(Human)
Topivert Pharma

US Patent
LigandPNGBDBM414113(US10435361, Example 1)
Affinity DataIC50: 657nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
US Patent