BDBM414197 US10435369, Example 84

SMILES Fc1ccc(cc1)S(=O)(=O)[C@@]12CC[C@H]([C@@H]1CCc1cc(ccc21)C(F)(C(F)(F)F)C(F)(F)F)C(=O)N1CCC2(CC(=O)N2)CC1

InChI Key InChIKey=NJEVGPWCPOIEBW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 414197   

TargetNuclear receptor ROR-gamma(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM414197(US10435369, Example 84)
Affinity DataIC50: 5nMAssay Description:Inverse agonist activity of potential ligands to RORγ was measured by inhibition of luminescence in a Gal4-luciferase reporter assay in Jurkat c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
US Patent