BDBM414267 US10435369, Example 154

SMILES CC1(C(=O)N[C@@H]2CC[C@@]3(S(=O)(=O)c4ccc(F)cc4)c4ccc(C(F)(C(F)(F)F)C(F)(F)F)cc4CC[C@@H]23)CCC(=O)N1

InChI Key InChIKey=DASFAWUVRWZPRE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 414267   

TargetNuclear receptor ROR-gamma(Human)
Bristol Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 414267BDBM414267(US10435369, Example 154)
Affinity DataIC50: 4nMAssay Description:Inverse agonist activity of potential ligands to RORγ was measured by inhibition of luminescence in a Gal4-luciferase reporter assay in Jurkat c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
US Patent