BDBM414269 US10435369, Example 156

SMILES O=C(N[C@@H]1CC[C@@]2(S(=O)(=O)c3ccc(F)cc3)c3ccc(C(F)(C(F)(F)F)C(F)(F)F)cc3CC[C@@H]12)C(O)C1CCOCC1

InChI Key InChIKey=AJEYKMCXGDWRGS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 414269   

TargetNuclear receptor ROR-gamma(Human)
Bristol Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 414269BDBM414269(US10435369, Example 156)
Affinity DataIC50: 4nMAssay Description:Inverse agonist activity of potential ligands to RORγ was measured by inhibition of luminescence in a Gal4-luciferase reporter assay in Jurkat c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
US Patent