BDBM414476 N-{2-[1-(3-Hydroxy-3-methylbutyl)piperidin-4-yl]-6-methoxy-2H-indazol-5-yl}-6-(trifluoromethyl)pyridine-2-carboxamide::US10435396, Example 52

SMILES COc1cc2nn(cc2cc1NC(=O)c1cccc(n1)C(F)(F)F)C1CCN(CCC(C)(C)O)CC1

InChI Key InChIKey=SASRTTPKDCHCMK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 414476   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Bayer Pharma Aktiegesellschaft

US Patent
LigandPNGBDBM414476(N-{2-[1-(3-Hydroxy-3-methylbutyl)piperidin-4-yl]-6...)
Affinity DataIC50: 1nMAssay Description:For the assay, 11 different concentrations in the range from 20 μM to 0.073 nM were prepared from a 2 mM solution of the test substance in DMSO....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
US Patent