BDBM414565 US10435400, Compound Z-107
SMILES CCN(CC)CCN(C)c1cc(OC)c(Nc2nccc(n2)-c2cnc3n(C)ccc3c2)cc1NC(=O)C=C
InChI Key InChIKey=MTVIRVHXMSHNRH-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 414565
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Shanghai Haiyan Pharmaceutical Technology
US Patent
Shanghai Haiyan Pharmaceutical Technology
US Patent
Affinity DataIC50: 16nMAssay Description:The inhibitory effects of compounds to be tested on double mutant EGFR kinase (EGFR T790M/L858R Kinase) (Invitrogen, PV4879) and wild-type EGFR kinas...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [T790M,L858R](Homo sapiens (Human))
Shanghai Haiyan Pharmaceutical Technology
US Patent
Shanghai Haiyan Pharmaceutical Technology
US Patent
Affinity DataIC50: 4nMAssay Description:The inhibitory effects of compounds to be tested on double mutant EGFR kinase (EGFR T790M/L858R Kinase) (Invitrogen, PV4879) and wild-type EGFR kinas...More data for this Ligand-Target Pair