BDBM414829 (6R,6aS,7aS,10aS,11aR)-14- (cyclopropylmethyl)-10-ethyl-2,6a- dihydroxy-5,6,6a,7,7a,8,10a,11- octahydro-6,11a-(epiminoethano)- naphtho[2,1-f]indol-9(10H)-one::US10435406, Compound 16

SMILES CCN1[C@H]2C[C@]34CCN(CC5CC5)[C@H](Cc5ccc(O)cc35)[C@]4(O)C[C@H]2CC1=O

InChI Key InChIKey=HKRZLNFUFCOSJH-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 414829   

TargetKappa-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM414829((6R,6aS,7aS,10aS,11aR)-14- (cyclopropylmethyl)-10-...)
Affinity DataKi:  0.310nMAssay Description:Membranes from recombinantHEK-293 cells, CHO or U-2 OS cells expressing the recombinant human κ opioid receptor (κ) were prepared by lysing...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
US Patent