BDBM415462 (Scheme C) (2R,3S,4R,5R)-2-((R)-(3,4-difluorophenyl)(hydroxy)methyl)-5-(4-methyl-7H-pyrrolo[2,3-d]pyrimidin-7-yl)tetrahydrofuran-3,4-diol (C-12)::US10428104, Example 9

SMILES O[C@@H]([C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ccc2c(Cl)ncnc12)c1ccc(F)c(F)c1

InChI Key InChIKey=URTKLNGRHRHVFG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 415462   

TargetProtein arginine N-methyltransferase 5(Human)
Pfizer

US Patent
LigandPNGBDBM415462(US10428104, Example 9 | (Scheme C) (2R,3S,4R,5R)-2...)
Affinity DataIC50: 3nMAssay Description:Compounds were solubilized in DMSO and serially diluted, using 3-fold dilutions, into 100% DMSO at a concentration 50-fold greater than the desired a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
US Patent