BDBM415563 (2R,3S,4R,5R)-2-((R)-amino(3,4-difluorophenyl)methyl)-5-(4-methyl-7H-pyrrolo[2,3-d]pyrimidin-7-yl)tetrahydrofuran-3,4-diol (SS-4)::US10428104, Example 94

SMILES Cc1ncnc2n(ccc12)[C@@H]1O[C@H]([C@H](N2C(=O)c3ccccc3C2=O)c2ccc(F)c(F)c2)[C@H]2OC(C)(C)O[C@@H]12

InChI Key InChIKey=JSCZHIYLUJDLFJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 415563   

TargetProtein arginine N-methyltransferase 5(Human)
Pfizer

US Patent
LigandPNGBDBM415563(US10428104, Example 94 | (2R,3S,4R,5R)-2-((R)-amin...)
Affinity DataIC50: 9nMAssay Description:Compounds were solubilized in DMSO and serially diluted, using 3-fold dilutions, into 100% DMSO at a concentration 50-fold greater than the desired a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
US Patent