BDBM415566 (2R,3R,4S,5R)-2-(4-(difluoromethyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-5-((R)-(3,4-difluorophenyl)(hydroxy)methyl)tetrahydrofuran-3,4-diol (UU-3)::US10428104, Example 97

SMILES O[C@@H]([C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ccc2c(ncnc12)C(F)F)c1ccc(F)c(F)c1

InChI Key InChIKey=ZWASKMNIRRUFIG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 415566   

TargetProtein arginine N-methyltransferase 5(Human)
Pfizer

US Patent
LigandPNGBDBM415566(US10428104, Example 97 | (2R,3R,4S,5R)-2-(4-(diflu...)
Affinity DataIC50: 30nMAssay Description:Compounds were solubilized in DMSO and serially diluted, using 3-fold dilutions, into 100% DMSO at a concentration 50-fold greater than the desired a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
US Patent