BDBM415772 US10442772, Example 2-160-2

SMILES COC(=O)CCc1cc2nc(Nc3ccc(cc3)C(C)C)n([C@H]3C[C@@H](C)CC(C)(C)C3)c2cc1C

InChI Key InChIKey=MLDANPMHBOUZEX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 415772   

TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM415772(US10442772, Example 2-160-2)
Affinity DataIC50: 30nMAssay Description:The biochemical reactions were performed at 32° C. in 384-well plates using a reaction volume of 41 μL and the following assay buffer conditions...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
US Patent