BDBM416423 (R)-1-ethyl-N-(1-(4-(ethylsulfonyl)phenyl)-2-hydroxyethyl)-2-((5-(trifluoromethyl)pyridin-2-yl)methyl)-1H-indole-5-carboxamide::US10301261, Compound IN-9::US10829448, Compound IN-9

SMILES CCn1c(Cc2ccc(cn2)C(F)(F)F)cc2cc(ccc12)C(=O)N[C@@H](CO)c1ccc(cc1)S(=O)(=O)CC

InChI Key InChIKey=YFCJJKIRQQREGX-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 416423   

TargetNuclear receptor ROR-gamma(Human)
Vitae Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 416423BDBM416423((R)-1-ethyl-N-(1-(4-(ethylsulfonyl)phenyl)-2-hydro...)
Affinity DataKi: <100nMAssay Description:Compounds described herein were tested for ability to bind to RORγ in a cell-free competition assay with commercially available radio-ligand (RL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2021
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Vitae Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 416423BDBM416423((R)-1-ethyl-N-(1-(4-(ethylsulfonyl)phenyl)-2-hydro...)
Affinity DataKi: <100nMAssay Description:Compounds described herein were tested for ability to bind to RORγ in a cell-free competition assay with commercially available radio-ligand (RL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
US Patent