BDBM416475 1-cyclopropyl-N-((5-(ethylsulfoyl)pyridin-2-yl)methyl)-2-(((1r,4r)-4-(trifluoromethyl)cyclohexyl)methyl)-1H-benzo[d]imidazole-5-carboxamide1-cyclopropyl-N-((5-(ethylsulfonyl)pyridin-2-yl)methyl)-2-(((1s,4s)-4-(trifluoromethyl)cyclohexyl)methyl)-1H-benzo[d]imidazole-5-carboxamide::US10301261, Compound BE-27.1::US10301261, Compound BE-27.2
SMILES CCS(=O)(=O)c1ccc(CNC(=O)c2ccc3n(C4CC4)c(C[C@H]4CC[C@@H](CC4)C(F)(F)F)nc3c2)nc1
InChI Key InChIKey=XVJHEHNTOLQCJT-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 416475
Affinity DataKi: <100nMAssay Description:Compounds described herein were tested for ability to bind to RORγ in a cell-free competition assay with commercially available radio-ligand (RL...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Compounds described herein were tested for RORγ inverse agonist activity in a cell-based, transcriptional activity assay. Secreted Nanoluc lucif...More data for this Ligand-Target Pair
Affinity DataKi: <100nMAssay Description:Compounds described herein were tested for ability to bind to RORγ in a cell-free competition assay with commercially available radio-ligand (RL...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Compounds described herein were tested for RORγ inverse agonist activity in a cell-based, transcriptional activity assay. Secreted Nanoluc lucif...More data for this Ligand-Target Pair