BDBM41658 1-(4-chlorophenyl)-N-(2-oxolanylmethyl)methanesulfonamide::1-(4-chlorophenyl)-N-(oxolan-2-ylmethyl)methanesulfonamide::1-(4-chlorophenyl)-N-(tetrahydro-2-furanylmethyl)methanesulfonamide::1-(4-chlorophenyl)-N-(tetrahydrofurfuryl)methanesulfonamide::MLS000099995::SMR000081216::cid_2973451

SMILES Cc1cc(N2CCOC[C@@H]2C(F)(F)F)cc(F)c1C(=O)N[C@@H](Cc1ccc(-n2c(=O)c3cc(N(C)C)ncc3n(C)c2=O)c2ncccc12)C(=O)O

InChI Key InChIKey=KJGDRASVEJHULE-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 41658   

TargetIntegrin alpha-4/beta-7(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 41658BDBM41658(US11116760, Example 416)
Affinity DataEC50:  0.126nMAssay Description:The CHO cell line was cultured in T-175 flasks at 37 degrees C and 95% relative humidity (RH). The growth media consisted of Dulbecco's Modified ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details
US Patent