BDBM416660 US10323013, Compound 38::allyl 8-hydroxy-7-(2-(methylsulfonyl)vinyl)-5-oxo-4,5-dihydro-1H-chromeno[3,4-c]pyridine-3(2H)-carboxylate

SMILES CS(=O)(=O)C=Cc1c(O)ccc2c3CCN(Cc3c(=O)oc12)C(=O)OCC=C

InChI Key InChIKey=WYERFLMCNLUHCY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 416660   

TargetSerine/threonine-protein kinase/endoribonuclease IRE1(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandPNGBDBM416660(US10323013, Compound 38 | allyl 8-hydroxy-7-(2-(me...)
Affinity DataIC50: 2.00E+4nMAssay Description:All compounds were evaluated by FRET-suppression assay in side-by-side experiments using 21b as a control inhibitor (Table 2). Protection of the alde...More data for this Ligand-Target Pair
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Date in BDB:
8/24/2020
Entry Details
US Patent