BDBM417067 US10456394, Example 5

SMILES ONC(=O)c1ccc(CN2CCCc3cc(F)ccc23)cc1

InChI Key InChIKey=XQWWNFXYWSZYTD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 417067   

TargetHistone deacetylase 6(Human)
University of Illinois

US Patent
LigandPNGBDBM417067(US10456394, Example 5)
Affinity DataIC50: 5.05nMAssay Description:The effectiveness, or potency, of a present HDACI with respect to inhibiting the activity of an HDAC is measured by an IC50 value. The quantitative I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
University of Illinois

US Patent
LigandPNGBDBM417067(US10456394, Example 5)
Affinity DataIC50: 5.24E+3nMAssay Description:The effectiveness, or potency, of a present HDACI with respect to inhibiting the activity of an HDAC is measured by an IC50 value. The quantitative I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
US Patent