BDBM417075 2-oxo-4-(2-phenoxyethoxy)-2H-[1,3'-bipyridine]-5'-carbonitrile::US10399948, Compound 26

SMILES O=c1cc(OCCOc2ccccc2)ccn1-c1cncc(c1)C#N

InChI Key InChIKey=CGYUDYXFOJDAOB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 417075   

TargetMetabotropic glutamate receptor 3(Rat)
Vanderbilt University

US Patent
LigandPNGBDBM417075(2-oxo-4-(2-phenoxyethoxy)-2H-[1,3'-bipyridine]-5'-...)
Affinity DataIC50: 3.41E+3nMAssay Description:Gα15/TREx cells stably expressing rat mGlu3 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 μL of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Vanderbilt University

US Patent
LigandPNGBDBM417075(2-oxo-4-(2-phenoxyethoxy)-2H-[1,3'-bipyridine]-5'-...)
Affinity DataIC50: 3.00E+4nMAssay Description:Gα15 HEK293 cells stably expressing rat mGlu2 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 μL of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
US Patent