BDBM417104 1-(4-fluorophenyl)-4-(2-((3-fluoropyridin-2-yl)oxy)ethoxy)pyridin-2(1H)-one::US10399948, Compound 51

SMILES Fc1ccc(cc1)-n1ccc(OCCOc2ncccc2F)cc1=O

InChI Key InChIKey=AOLLYVIFCUZOKM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 417104   

TargetMetabotropic glutamate receptor 3(Rat)
Vanderbilt University

US Patent
LigandPNGBDBM417104(1-(4-fluorophenyl)-4-(2-((3-fluoropyridin-2-yl)oxy...)
Affinity DataIC50: 1.28E+3nMAssay Description:Gα15/TREx cells stably expressing rat mGlu3 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 μL of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Vanderbilt University

US Patent
LigandPNGBDBM417104(1-(4-fluorophenyl)-4-(2-((3-fluoropyridin-2-yl)oxy...)
Affinity DataIC50: 3.00E+4nMAssay Description:Gα15 HEK293 cells stably expressing rat mGlu2 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 μL of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
US Patent