BDBM417119 US10456394, Example 14::US10456394, Example 15

SMILES COC(=O)c1ccc(CN2CCN(C(=O)OC(C)(C)C)c3ccccc23)cc1

InChI Key InChIKey=HTFNVIVUHXIJPN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 417119   

TargetHistone deacetylase 6(Human)
University of Illinois

US Patent
LigandPNGBDBM417119(US10456394, Example 14 | US10456394, Example 15)
Affinity DataIC50: 2.90nMAssay Description:The effectiveness, or potency, of a present HDACI with respect to inhibiting the activity of an HDAC is measured by an IC50 value. The quantitative I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
University of Illinois

US Patent
LigandPNGBDBM417119(US10456394, Example 14 | US10456394, Example 15)
Affinity DataIC50: 39.3nMAssay Description:The effectiveness, or potency, of a present HDACI with respect to inhibiting the activity of an HDAC is measured by an IC50 value. The quantitative I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
University of Illinois

US Patent
LigandPNGBDBM417119(US10456394, Example 14 | US10456394, Example 15)
Affinity DataIC50: 6.69E+3nMAssay Description:The effectiveness, or potency, of a present HDACI with respect to inhibiting the activity of an HDAC is measured by an IC50 value. The quantitative I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
University of Illinois

US Patent
LigandPNGBDBM417119(US10456394, Example 14 | US10456394, Example 15)
Affinity DataIC50: 8.75E+3nMAssay Description:The effectiveness, or potency, of a present HDACI with respect to inhibiting the activity of an HDAC is measured by an IC50 value. The quantitative I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
US Patent