BDBM417121 US10456394, Example 16

SMILES ONC(=O)c1ccc(CN2CCSc3ccccc23)cc1

InChI Key InChIKey=YTMXNALITJPBCC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 417121   

TargetHistone deacetylase 6(Human)
University of Illinois

US Patent
LigandPNGBDBM417121(US10456394, Example 16)
Affinity DataIC50: 6.10nMAssay Description:The effectiveness, or potency, of a present HDACI with respect to inhibiting the activity of an HDAC is measured by an IC50 value. The quantitative I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
University of Illinois

US Patent
LigandPNGBDBM417121(US10456394, Example 16)
Affinity DataIC50: 7.94E+3nMAssay Description:The effectiveness, or potency, of a present HDACI with respect to inhibiting the activity of an HDAC is measured by an IC50 value. The quantitative I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
US Patent