BDBM417124 US10456394, Example 18::US10456394, Example 19

SMILES CC(C)(C)OC(=O)N1CC(=O)N(Cc2ccc(cc2)C(=O)NO)c2ccccc12

InChI Key InChIKey=PRCKFCQKCLSVQR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 417124   

TargetHistone deacetylase 6(Human)
University of Illinois

US Patent
LigandPNGBDBM417124(US10456394, Example 18 | US10456394, Example 19)
Affinity DataIC50: 1.20nMAssay Description:The effectiveness, or potency, of a present HDACI with respect to inhibiting the activity of an HDAC is measured by an IC50 value. The quantitative I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
University of Illinois

US Patent
LigandPNGBDBM417124(US10456394, Example 18 | US10456394, Example 19)
Affinity DataIC50: 33.6nMAssay Description:The effectiveness, or potency, of a present HDACI with respect to inhibiting the activity of an HDAC is measured by an IC50 value. The quantitative I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
University of Illinois

US Patent
LigandPNGBDBM417124(US10456394, Example 18 | US10456394, Example 19)
Affinity DataIC50: 1.05E+3nMAssay Description:The effectiveness, or potency, of a present HDACI with respect to inhibiting the activity of an HDAC is measured by an IC50 value. The quantitative I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
University of Illinois

US Patent
LigandPNGBDBM417124(US10456394, Example 18 | US10456394, Example 19)
Affinity DataIC50: 2.20E+4nMAssay Description:The effectiveness, or potency, of a present HDACI with respect to inhibiting the activity of an HDAC is measured by an IC50 value. The quantitative I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
US Patent