BDBM418606 N-[3-({[2-anilino-5- (trifluoromethyl)pyrimidin-4- yl]amino}methyl)pyridin-2-yl]-N- methylmethane-sulfonamide (50)::US10450297, Example 50
SMILES CN(c1ncccc1CNc1nc(Nc2ccccc2)ncc1C(F)(F)F)S(C)(=O)=O
InChI Key InChIKey=FBCYLDMQAGIHQR-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 418606
Affinity DataIC50: 0.590nMAssay Description:The in vitro activity of the compounds of the compounds of the invention may be determined by the following procedure. More particularly, the followi...More data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Inhibition of full-length FAK (unknown origin) with N-terminal NanoLuc-fusion expressed in HEK293T cells by NanoBRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Inhibition of full-length PYK2 (unknown origin) with C-terminal NanoLuc-fusion expressed in HEK293T cells by NanoBRET assayMore data for this Ligand-Target Pair
Affinity DataKd: 470nMAssay Description:Binding affinity to human recombinant PYK2 (amino acids 420-691) expressed in Escherichia coli, BL21 (DE3) assessed as equilibrium dissociation const...More data for this Ligand-Target Pair