BDBM418822 3-fluoro-4-({4-[({2- [methyl(methylsulfonyl)amino]pyridin-3- yl}methyl)amino]-5- (trifluoromethyl)pyrimidin-2- yl}amino)benzamide (322), formic acid salt::US10450297, Example 322

SMILES CN(c1ncccc1CNc1nc(Nc2ccc(cc2F)C(N)=O)ncc1C(F)(F)F)S(C)(=O)=O

InChI Key InChIKey=XJBGVRZQCGTLLJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 418822   

TargetFocal adhesion kinase 1 [410-689](Human)
Pfizer

US Patent
LigandPNGBDBM418822(3-fluoro-4-({4-[({2- [methyl(methylsulfonyl)amino]...)
Affinity DataIC50: 0.595nMAssay Description:The in vitro activity of the compounds of the compounds of the invention may be determined by the following procedure. More particularly, the followi...More data for this Ligand-Target Pair
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Date in BDB:
8/31/2020
Entry Details
US Patent