BDBM418889 N-[3-({[2-{[4-({[2-hydroxy-1- (hydroxymethyl)ethyl]amino}methyl) phenyl]amino}-5-(trifluoromethyl)pyrimidin- 4-yl]amino}methyl)pyridin-2-yl]-N- methylmethane-sulfonamide (389)::US10450297, Example 389

SMILES CN(c1ncccc1CNc1nc(Nc2ccc(CNC(CO)CO)cc2)ncc1C(F)(F)F)S(C)(=O)=O

InChI Key InChIKey=UARGBWWMGWMZIM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 418889   

TargetFocal adhesion kinase 1 [410-689](Human)
Pfizer

US Patent
LigandPNGBDBM418889(US10450297, Example 389 | N-[3-({[2-{[4-({[2-hydro...)
Affinity DataIC50: 0.595nMAssay Description:The in vitro activity of the compounds of the compounds of the invention may be determined by the following procedure. More particularly, the followi...More data for this Ligand-Target Pair
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Date in BDB:
8/31/2020
Entry Details
US Patent