BDBM419082 US10450301, Example 161

SMILES CC(C)CS(=O)(=O)N1CCc2cnc(cc2C1)C(=O)Nc1cccc(n1)-c1nnnn1[C@H](C)CO

InChI Key InChIKey=GNUHXGBXPHNWJS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 419082   

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Enanta Pharmaceuticals

US Patent
LigandPNGBDBM419082(US10450301, Example 161)
Affinity DataIC50: 5.5nMAssay Description:HTRF KinEASE-STK is a generic method for measuring serine/threonine kinase activities using a time-resolved fluorescence resonance energy transfer (T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details
US Patent