BDBM419114 (2-{[5-tert-Butyl-7-(3,3-difluoropyrrolidin-1-yl)-2H-[1,2,3]triazolo[4,5-d]pyrimidin-2-yl]methyl}phenyl)methanesulfonyl fluoride::US10450321, Example 2

SMILES CC(C)(C)c1nc(N2CCC(F)(F)C2)c2nn(Cc3ccccc3CS(F)(=O)=O)nc2n1

InChI Key InChIKey=GTMBDQSSOXUOSO-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 419114   

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM419114(US10450321, Example 2 | (2-{[5-tert-Butyl-7-(3,3-d...)
Affinity DataKi:  637nMAssay Description:The affinity of the compounds of the invention for cannabinoid receptors was determined using recommended amounts of membrane preparations (PerkinElm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details
US Patent

TargetCannabinoid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM419114(US10450321, Example 2 | (2-{[5-tert-Butyl-7-(3,3-d...)
Affinity DataKi: >1.00E+4nMAssay Description:The affinity of the compounds of the invention for cannabinoid receptors was determined using recommended amounts of membrane preparations (PerkinElm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details
US Patent