BDBM419119 2-[[5-tert-Butyl-7-(3,3-difluoropyrrolidin-1-yl)triazolo[4,5-d]pyrimidin-2-yl]methyl]-3-ethynylbenzenesulfonyl fluoride::US10450321, Example 7

SMILES CC(C)(C)c1nc(N2CCC(F)(F)C2)c2nn(Cc3c(cccc3S(F)(=O)=O)C#C)nc2n1

InChI Key InChIKey=SJNNSJCWGOHBOP-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 419119   

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM419119(US10450321, Example 7 | 2-[[5-tert-Butyl-7-(3,3-di...)
Affinity DataKi:  421nMAssay Description:The affinity of the compounds of the invention for cannabinoid receptors was determined using recommended amounts of membrane preparations (PerkinElm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details
US Patent

TargetCannabinoid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM419119(US10450321, Example 7 | 2-[[5-tert-Butyl-7-(3,3-di...)
Affinity DataKi: >1.00E+4nMAssay Description:The affinity of the compounds of the invention for cannabinoid receptors was determined using recommended amounts of membrane preparations (PerkinElm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details
US Patent