BDBM419231 N-(4-ethylphenyl)-N- isobutyl-3-(S- methylsulfonimidoyl)-4-(2- oxa-6-azaspiro[3.5]nonan- 6-yl)benzenesulfonamide::US10457637, Compound 109

SMILES CCc1ccc(cc1)N(CC(C)C)S(=O)(=O)c1ccc(N2CCCC3(COC3)C2)c(c1)S(C)(=N)=O

InChI Key InChIKey=ZBJHBBHEHQEDAY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 419231   

TargetNuclear receptor ROR-gamma(Human)
Galderma Research & Development

US Patent
LigandChemical structure of BindingDB Monomer ID 419231BDBM419231(N-(4-ethylphenyl)-N- isobutyl-3-(S- methylsulfonim...)
Affinity DataIC50: 1.00E+3nMAssay Description:The RORγ transactivation model was developed from the line HG5LN, which is a HeLa line that stably expresses a luciferase reporter gene controll...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2020
Entry Details
US Patent