BDBM419237 4-((1R,4R)-2-oxa-5- azabicyclo[2.2.1]heptan-5- yl)-N-(4-ethylphenyl)-N- isobutyl-3-(S- methylsulfonimidoyl) benzenesulfonamide::US10457637, Compound 115

SMILES CCc1ccc(cc1)N(CC(C)C)S(=O)(=O)c1ccc(N2C[C@H]3C[C@@H]2CO3)c(c1)S(C)(=N)=O

InChI Key InChIKey=LGDUQFPDWZJWSJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 419237   

TargetNuclear receptor ROR-gamma(Human)
Galderma Research & Development

US Patent
LigandChemical structure of BindingDB Monomer ID 419237BDBM419237(4-((1R,4R)-2-oxa-5- azabicyclo[2.2.1]heptan-5- yl)...)
Affinity DataIC50: 550nMAssay Description:The RORγ transactivation model was developed from the line HG5LN, which is a HeLa line that stably expresses a luciferase reporter gene controll...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2020
Entry Details
US Patent