BDBM419287 5-tert-Butyl-7-(3-isothiocyanatopyrrolidin-1-yl)-3-[(4-methyl-1,2,5-oxadiazol-3-yl)methyl]-3H-[1,2,3]triazolo[4,5-d]pyrimidine::US10457685, Example 16

SMILES Cc1nonc1Cn1nnc2c(nc(nc12)C(C)(C)C)N1CCC(C1)N=C=S

InChI Key InChIKey=SXKFHRIHLDDNIF-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 419287   

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM419287(5-tert-Butyl-7-(3-isothiocyanatopyrrolidin-1-yl)-3...)
Affinity DataKi:  426nMAssay Description:he affinity of the compounds of the invention for cannabinoid receptors was determined using recommended amounts of membrane preparations (PerkinElme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2020
Entry Details
US Patent

TargetCannabinoid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM419287(5-tert-Butyl-7-(3-isothiocyanatopyrrolidin-1-yl)-3...)
Affinity DataKi: >1.00E+4nMAssay Description:he affinity of the compounds of the invention for cannabinoid receptors was determined using recommended amounts of membrane preparations (PerkinElme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2020
Entry Details
US Patent