BDBM420031 2-cyclopentyl-N-(((S)-1-isopropylpyrrolidin-2- yl)methyl)-10-methyl-1-oxo-1,2,3,4- tetrahydropyrazino[1,2-a]indole-4-carboxamide::US10487087, Compound 3

SMILES CC(C)N1CCC[C@H]1CNC(=O)C1CN(C2CCCC2)C(=O)c2c(C)c3ccccc3n12

InChI Key InChIKey=RMRHNKRVVWQAJH-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 420031   

TargetGlucagon-like peptide 1 receptor(Human)
Vanderbilt University

US Patent
LigandPNGBDBM420031(2-cyclopentyl-N-(((S)-1-isopropylpyrrolidin-2- yl)...)
Affinity DataEC50:  5.70E+3nMAssay Description:To assess the effects of test compounds on GLP-1 or glucagon potency and efficacy, a high-throughput calcium mobilization assay was used essentially ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
9/20/2020
Entry Details
US Patent

TargetGlucagon-like peptide 1 receptor(Human)
Vanderbilt University

US Patent
LigandPNGBDBM420031(2-cyclopentyl-N-(((S)-1-isopropylpyrrolidin-2- yl)...)
Affinity DataEC50:  1.10E+4nMAssay Description:To assess the effects of test compounds on GLP-1 or glucagon potency and efficacy, a high-throughput calcium mobilization assay was used essentially ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
9/20/2020
Entry Details
US Patent