BDBM420051 (S)-10-cyano-2-cyclopentyl-N-((1- isopropylpyrrolidin-2-yl)methyl)-1-oxo-1,2- dihydropyrazino[1,2-a]indole-4-carboxamide::US10487087, Compound 16

SMILES CC(C)N1CCC[C@H]1CNC(=O)c1cn(C2CCCC2)c(=O)c2c(C#N)c3ccccc3n12

InChI Key InChIKey=QJTHSQUYWKKPFT-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 420051   

TargetGlucagon-like peptide 1 receptor(Human)
Vanderbilt University

US Patent
LigandPNGBDBM420051((S)-10-cyano-2-cyclopentyl-N-((1- isopropylpyrroli...)
Affinity DataEC50:  1.90E+3nMAssay Description:To assess the effects of test compounds on GLP-1 or glucagon potency and efficacy, a high-throughput calcium mobilization assay was used essentially ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
9/20/2020
Entry Details
US Patent