BDBM420052 (S)-2-cyclopentyl-N-((1-isopropylpyrrolidin-2- yl)methyl)-1-oxo-10-vinyl-1,2-dihydro- pyrazino[1,2-a]indole-4-carboxamide::US10487087, Compound 17

SMILES CC(C)N1CCC[C@H]1CNC(=O)c1cn(C2CCCC2)c(=O)c2c(C=C)c3ccccc3n12

InChI Key InChIKey=GELZHLAECYQMLG-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 420052   

TargetGlucagon-like peptide 1 receptor(Human)
Vanderbilt University

US Patent
LigandPNGBDBM420052((S)-2-cyclopentyl-N-((1-isopropylpyrrolidin-2- yl)...)
Affinity DataEC50:  9.60E+3nMAssay Description:To assess the effects of test compounds on GLP-1 or glucagon potency and efficacy, a high-throughput calcium mobilization assay was used essentially ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
9/20/2020
Entry Details
US Patent