BDBM420108 (7S) N-(2-Hydroxy-2-methylpropyl)-N-methyl-4-(pyrazolo[1,5-a]pyridin-5-ylamino)-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidine-7-carboxamide::US10487092, Example 19

SMILES CN(CC(C)(C)O)C(=O)[C@H]1CCc2c(C1)sc1ncnc(Nc3ccn4nccc4c3)c21

InChI Key InChIKey=IRYRYHGFOPXVDT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 420108   

LigandChemical structure of BindingDB Monomer ID 420108BDBM420108((7S) N-(2-Hydroxy-2-methylpropyl)-N-methyl-4-(pyra...)
Affinity DataIC50: 21nMAssay Description:A recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accession n...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
9/20/2020
Entry Details
US Patent