BDBM420129 (1S,4S)-2-Oxa-5-azabicyclo[2.2.1]hept-5-yl[(7S)-4-(pyrazolo[1,5-a]pyridin-5-ylamino)-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-7-yl]methanone::US10487092, Example 36

SMILES O=C([C@H]1CCc2c(C1)sc1ncnc(Nc3ccn4nccc4c3)c21)N1C[C@@H]2C[C@H]1CO2

InChI Key InChIKey=BZZSAKHWUSWLSE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 420129   

LigandChemical structure of BindingDB Monomer ID 420129BDBM420129((1S,4S)-2-Oxa-5-azabicyclo[2.2.1]hept-5-yl[(7S)-4-...)
Affinity DataIC50: 91nMAssay Description:A recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accession n...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
9/20/2020
Entry Details
US Patent