BDBM420317 5-Bromo-3-(sec-butoxy)-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-2-methylbenzamide::US10478426, Example 20::US10478426, Example 44
SMILES CCC(C)Oc1cc(Br)cc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C
InChI Key
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 420317
TargetHistone-binding protein RBBP4/Polycomb protein EED/Polycomb protein SUZ12/Zinc finger protein AEBP2(Homo sapiens (Human))
Glaxosmithkline
US Patent
Glaxosmithkline
US Patent
Affinity DataIC50: 316nMAssay Description:Compounds contained herein were evaluated for their ability to inhibit the methyltransferase activity of EZH2 within the PRC2 complex. Human PRC2 com...More data for this Ligand-Target Pair
Ligand Info
TargetHistone-binding protein RBBP4/Polycomb protein EED/Polycomb protein SUZ12/Zinc finger protein AEBP2(Homo sapiens (Human))
Glaxosmithkline
US Patent
Glaxosmithkline
US Patent
Affinity DataIC50: 13nMAssay Description:Compounds contained herein were evaluated for their ability to inhibit the methyltransferase activity of EZH2 within the PRC2 complex. Human PRC2 com...More data for this Ligand-Target Pair
Ligand Info