BDBM42057 3-Methyl-N-[4-(3-pyridin-3-yl-acryloyl)-phenyl]-benzamide::3-methyl-N-[4-[(E)-1-oxo-3-(3-pyridinyl)prop-2-enyl]phenyl]benzamide::3-methyl-N-[4-[(E)-3-(3-pyridyl)acryloyl]phenyl]benzamide::3-methyl-N-[4-[(E)-3-pyridin-3-ylprop-2-enoyl]phenyl]benzamide::MLS000564001::SMR000175722::cid_5335764

SMILES N1(C=NC=C1)C1=CC=C(C=N1)/C=C/C=1C=NC(=NC1)N1[C@H](CN(CC1)C1=NC=NC=C1)CO

InChI Key InChIKey=NCBNDSKEBCKKKW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 42057   

TargetAlpha-synuclein(Human)
8932 Hightail Drive

WIPO
LigandChemical structure of BindingDB Monomer ID 42057BDBM42057((R,E)-(1-(5-(2-(6-(1H-imidazol-1-yl)pyridin-3-yl)v...)
Affinity DataKi:  0.5nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details
WIPO WO2024186584

TargetAmyloid-beta precursor protein(Human)
8932 Hightail Drive

WIPO
LigandChemical structure of BindingDB Monomer ID 42057BDBM42057((R,E)-(1-(5-(2-(6-(1H-imidazol-1-yl)pyridin-3-yl)v...)
Affinity DataKi:  120nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details
WIPO WO2024186584