BDBM421152 2-((3-(4-Aminoimidazo[2,1-f][1,2,4]triazin-7-yl)-4- methylphenyl)sulfonyl)-6-methyl-2,6-diazaspiro[3.4]octan- 5-one::US10479795, Example 195

SMILES CN1CCC2(CN(C2)S(=O)(=O)c2ccc(C)c(c2)-c2cnc3c(N)ncnn23)C1=O

InChI Key InChIKey=ZQZKXYBLBZGEPC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 421152   

LigandPNGBDBM421152(US10479795, Example 195 | 2-((3-(4-Aminoimidazo[2,...)
Affinity DataIC50: 100nMAssay Description:PI3K-γ:[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.)....More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
9/26/2020
Entry Details
US Patent

LigandPNGBDBM421152(US10479795, Example 195 | 2-((3-(4-Aminoimidazo[2,...)
Affinity DataIC50: 500nMAssay Description:PI3Kδ:[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
9/26/2020
Entry Details
US Patent