BDBM421168 7-(5-((cis-Hexahydro-5H-furo[2,3-c]pyrrol-5-yl)sulfonyl)- 2-methylphenyl)imidazo[2,1-f][1,2,4]triazin-4-amine::US10479795, Example 211

SMILES Cc1ccc(cc1-c1cnc2c(N)ncnn12)S(=O)(=O)N1C[C@@H]2CCO[C@@H]2C1

InChI Key InChIKey=VKNUALJWJOKEOG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 421168   

LigandPNGBDBM421168(US10479795, Example 211 | 7-(5-((cis-Hexahydro-5H-...)
Affinity DataIC50: 100nMAssay Description:PI3K-γ:[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.)....More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
9/26/2020
Entry Details
US Patent

LigandPNGBDBM421168(US10479795, Example 211 | 7-(5-((cis-Hexahydro-5H-...)
Affinity DataIC50: 2.00E+3nMAssay Description:PI3Kδ:[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
9/26/2020
Entry Details
US Patent