BDBM421170 (S)-2-(1-((3-(4-Aminoimidazo[2,1-f][1,2,4]triazin-7-yl)-4- methylphenyl)sulfonyl)pyrroldiin-2-yl)propan-2-ol::US10479795, Example 213

SMILES Cc1ccc(cc1-c1cnc2c(N)ncnn12)S(=O)(=O)N1CCC[C@H]1C(C)(C)O

InChI Key InChIKey=WLGZVOKNAZTAHG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 421170   

LigandPNGBDBM421170(US10479795, Example 213 | (S)-2-(1-((3-(4-Aminoimi...)
Affinity DataIC50: 100nMAssay Description:PI3K-γ:[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.)....More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
9/26/2020
Entry Details
US Patent

LigandPNGBDBM421170(US10479795, Example 213 | (S)-2-(1-((3-(4-Aminoimi...)
Affinity DataIC50: 2.00E+3nMAssay Description:PI3Kδ:[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
9/26/2020
Entry Details
US Patent