BDBM421179 7-(2-methyl-5-((8-methyl-5,6-dihydro-[1,2,4]triazolo[4,3- a]pyrazin-7(8H)-yl)sulfonyl)phenyl)imidazo[2,1- f][1,2,4]triazin-4-amine::US10479795, Example 222

SMILES CC1N(CCn2cnnc12)S(=O)(=O)c1ccc(C)c(c1)-c1cnc2c(N)ncnn12

InChI Key InChIKey=BGVALWAXTSHODU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 421179   

LigandPNGBDBM421179(US10479795, Example 222 | 7-(2-methyl-5-((8-methyl...)
Affinity DataIC50: 100nMAssay Description:PI3K-γ:[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.)....More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
9/26/2020
Entry Details
US Patent

LigandPNGBDBM421179(US10479795, Example 222 | 7-(2-methyl-5-((8-methyl...)
Affinity DataIC50: 100nMAssay Description:PI3Kδ:[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
9/26/2020
Entry Details
US Patent