BDBM421491 US10508083, Example 118::US11292766, Example 118::cis-N-ethyl-3- ((methylsulfonyl)amino)-2-(((1- (pyrimidin-2-yl)piperidin-4- yl)oxy)methyl)piperidine-1- carboxamide

SMILES CCNC(=O)N1CCC[C@H](NS(C)(=O)=O)[C@@H]1COC1CCN(CC1)c1ncccn1

InChI Key InChIKey=RIVSHGVTJDTCGC-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 421491   

TargetOrexin receptor type 2(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM421491(US10508083, Example 118 | cis-N-ethyl-3- ((methyls...)
Affinity DataEC50:  4.60nMAssay Description:Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2022
Entry Details
US Patent

TargetOrexin receptor type 2(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM421491(US10508083, Example 118 | cis-N-ethyl-3- ((methyls...)
Affinity DataEC50:  4.60nMAssay Description:Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2020
Entry Details
US Patent