BDBM421644 3-((5-cyano-6-(trifluoromethyl)-1H- benzo[d]imidazol-2-yl)(methyl)amino)-N- hydroxybenzamide::US10508088, Example 9-1::US10538496, Compound 9-1

SMILES CN(c1nc2cc(C#N)c(cc2[nH]1)C(F)(F)F)c1cccc(c1)C(=O)NO

InChI Key InChIKey=QTNGXBRYVOOOCJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 421644   

TargetHistone deacetylase 11(Human)
Forma Therapeutics

US Patent
LigandPNGBDBM421644(3-((5-cyano-6-(trifluoromethyl)-1H- benzo[d]imidaz...)
Affinity DataIC50: <500nMAssay Description:The probe binding HDAC11 assay was performed using a time resolved fluorescence (TRF) assay format. Recombinant N-terminal GST tag full-length human ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetHistone deacetylase 11(Human)
Forma Therapeutics

US Patent
LigandPNGBDBM421644(3-((5-cyano-6-(trifluoromethyl)-1H- benzo[d]imidaz...)
Affinity DataIC50: <500nMAssay Description:This example describes in vitro inhibition properties of exemplary HDAC11 inhibitors for various HDACs. HDAC inhibition assays were performed using a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent